Researchers at Harvard and other leading institutions have uncovered the surprising role of a tiny molecule inside your cells that helps determine how you age — influencing everything from daily energy and memory, to metabolism and even how well your body repairs itself.
This molecule is called NAD⁺, and your levels naturally decline as you get older. By age 50, you may have only half as much as you did in your 20s — which can mean more fatigue, slower recovery, brain fog, and subtle signs of ageing.
Recent studies suggest that certain natural compounds may help support and restore NAD⁺ levels. Early research shows potential benefits for energy, brain function, cardiovascular health, and overall cellular repair.
In this article, we’ll break down
- What is NAD⁺?
- Can I take NAD⁺ supplements to boost NAD⁺ levels?
- NMN vs NR?
- Why we use NMN
- Benefits of NMN
- Real results from our customer study
- How to choose the best NMN supplement?
- Pairing NMN with other supplements
- How much NMN should I take?
What is NAD⁺?
NAD⁺ is a fundamental molecule involved in hundreds of metabolic processes throughout the body. Its most crucial roles include converting nutrients into energy and fuelling enzymes that protect and repair DNA. In many ways, NAD⁺ is essential for maintaining healthy energy levels and keeping your body’s repair and recovery systems running smoothly.
Unfortunately, NAD⁺ levels naturally decline with age. By the time you reach 50, your NAD⁺ levels may be about half of what they were at age 20. While you can survive with low NAD⁺, it can accelerate ageing and reduce your healthspan — the number of years you feel strong, healthy, and mentally sharp.
As your NAD⁺ levels dip, so does your ability to perform efficiently. Think of this like your body’s vitality.
Signs of low NAD⁺ levels
- Fatigue and low energy levels
- Brain fog or difficulty concentrating
- Reduced physical endurance and strength
- Slower recovery from exercise or injuries
- Poor sleep quality
- Weakened immune function
- Premature signs of ageing, such as skin changes
Easy to dismiss as “just ageing”, but they add up: afternoon slumps, fading focus, slower recovery.
Thankfully, research shows that these ageing signs can be slowed — or even reversed — by restoring your NAD⁺ to higher levels. Doing this has been shown to have multiple benefits, such as organ health, brain health, cardiovascular health and even your skin’s elasticity.
Can I take NAD⁺ supplements to boost NAD⁺ levels?
Direct NAD⁺ supplements aren’t effectively absorbed by the body in oral form. While NAD⁺ IV infusions exist, they can be uncomfortable — causing nausea, cramping, and sensitivity to light and sound — and aren’t practical for daily use.
Scientists have instead focused on molecules that naturally convert into NAD⁺ once inside the body. Two of the most studied are NMN and NR. Research shows that supplementing with either can raise NAD⁺ levels, supporting the cellular processes that rely on this essential coenzyme.
NMN vs NR?
NMN and NR are both precursors to NAD⁺, found in small amounts in foods and naturally produced in the body. They act as the building blocks for NAD⁺ production once consumed. However, important differences exist:
- NMN contains nicotinamide (vitamin B3), ribose (a sugar molecule), and a phosphate group. It’s one step closer to becoming NAD⁺ than NR.
- NR lacks the phosphate group, making it a smaller molecule, but it must be converted into NMN before becoming NAD⁺.
Studies have shown that NMN is more stable in the bloodstream than NR, and is absorbed efficiently by cells.
Experts like Dr David Sinclair of Harvard Medical School and Dr Shin-ichiro Imai of Washington University have been strong advocates of NMN’s potential for supporting longevity and metabolic health.
Why the Supplement Industry Chooses NMN
- NMN is already one step closer to NAD⁺ than NR, allowing for faster and more efficient conversion.
- NMN remains stable in blood and resists rapid breakdown, unlike NR. NR is shown to break down quickly according to studies in mice.
- NMN has shown a wider range of benefits in clinical and preclinical studies, particularly for energy metabolism, cardiovascular health, and cognitive function.
- Leading longevity researchers, including Harvard’s Dr David Sinclair, have publicly stated they take NMN themselves.
Things You Should Know About NMN Before You Buy
While NMN supplementation can boost NAD⁺, not all forms absorb equally.
Bioavailability — how much actually reaches your bloodstream — is what drives results.
A recent double-blind study from Kiryu University’s Department of Nutrition in Japan compared standard NMN (350 mg/day) with liposomal NMN over four weeks.
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Findings: Liposomal NMN produced a significantly greater increase in blood NAD⁺ than both standard NMN and placebo (by 84%); standard NMN was not significantly different from placebo at four weeks.
This is why we use a liquid liposomal NMN for better uptake and more consistent results.
Benefits of Liposomal NMN
Liposomal delivery helps NMN cross the digestive tract intact and reach the bloodstream more efficiently. Once converted to NAD⁺, it supports mitochondrial energy (ATP) production and activates sirtuins involved in DNA repair, inflammation control, and stress resilience.
By sustaining NAD⁺, liposomal NMN helps maintain cellular energy and repair capacity. Reported benefits include:
- Higher, steadier energy and less fatigue
- Sharper focus and mental clarity
- Better exercise performance and faster recovery
- Improved sleep quality
- Healthier weight control and insulin sensitivity
- Support for female reproductive health
If you were to use a standard NMN capsule or powder, you would be waiting for months for these benefits — if they ever came at all.
Real results from our own customer study
We tested our Swiss-made, liposomal NMN with a group of customers over a 12-week period. Results exceeded expectations:
- 92% reported improved energy and focus
- 81% noticed a boost in overall wellbeing
- 79% experienced enhanced mood and emotional balance
- 95% preferred a liquid supplement over a pill or capsule
Customers reported feeling sharper in the morning, recovering faster from workouts, and experiencing more consistent energy throughout the day after taking Pure Anti-Age NMN Liposomal.
How to Choose the Best NMN Supplement?
1. Purity is important — but absorption is key
Many supplements on the market contain less NMN than claimed, or none at all. Our NMN is produced in Switzerland with over 99% purity, verified by third-party lab testing. Our liposomal process will not work with impurities, further enhancing our quality standards.
There is no point taking something if your body isn’t going to use it. This is why NMN using a liposomal delivery is the key to better results and saving you money.
2. Reputable manufacturing
The supplement industry is poorly regulated, and many products come from substandard factories, risking contamination or shorter shelf life.
Our NMN goes through an advanced liposomal process that is patented. It can only be done in the highest quality labs that carry both GMP and ISO 22,000 certification. It is the product of 15 years of clinical research, 4 global patents, and a CPhI award for formulation.
3. Protection from degradation
Liposomal encapsulation shields NMN from stomach acid for superior uptake, while Miron glass bottles block light to help maintain potency and freshness.
4. Combo with synergistic supplements
While supplementing with NMN alone already boosts NAD⁺ levels, you can achieve much better results by targeting NAD⁺ level increase and maintenance through multiple approaches.
For example, using antioxidants to reduce oxidative degradation of NAD⁺ increases the NAD⁺ level your body can retain over time and can make your NMN supplementation more effective.
We offer two solid choices to augment your longevity goals, both packed with micellisation technology to absorb completely like our NMN liposomal.
- Pure Vitality CoQ10 + Vitamin E — supports mitochondrial health and reduces oxidative stress.
- Pure Beginnings Spermidine + Folic Acid — promotes cellular renewal and overall vitality.
Does NMN have side effects?
NMN is recognised as safe, with no significant side effects reported according to current research.
Animal studies have shown that even at high doses, NMN is non-toxic, and long-term use in mice for up to one year has not resulted in any adverse effects. Early human clinical trials have also been promising, suggesting that NMN is well-tolerated in single doses.
The impact of NMN on patients with serious illnesses such as cancer is not well studied yet, and anyone affected by these illnesses should consult their doctor before consuming a supplement like NMN.
How much of Pure Anti-Age NMN Liposomal should I take?
Most studies suggest 250–500 mg/day, but because we use a liposomal technology, 5 drops of Pure Anti-Age is equal to a 600 mg dose.
The formula is streamlined (no unnecessary additives you’d find in powders and capsules), designed for rapid uptake, so a small, consistent daily dose goes a long way.
With our Pure Anti-Age NMN, you also get:
- Expert formulation perfected over 15 years of research by Swiss longevity experts
- The highest purity possible (beyond 99%) because of the demands of our nano-liposomal technology
- No fillers or buffers found in capsules or powders
- 100% vegan and suitable for any diet type
- Proven efficacy for elevating and sustaining NAD⁺ levels
- Perfect to pair with other supplements for longevity
Bottom line: if you’re going to use NMN, choose a format that actually reaches your bloodstream. Our Swiss-made, liposomal NMN (>99% purity) is simple and efficient — no fillers, just 5 drops in any drink once daily for high absorption and steady support of NAD⁺. It pairs well with our CoQ10 + Vitamin E liquid drops or our Spermidine + Folic Acid drops, and offers a low-dose, high-uptake way to back your energy, focus, and recovery.